Intact Genomics had two poster presentations of our recent progresses on drug discovery R&D:
P84 – FUNGAL ARTIFICIAL CHROMOSOMES ACTIVATE THE CRYPTIC BIOSYNTHETIC GENE CLUSTER OF STROBILURINS, A POTENT AGRICULTURAL FUNGICIDE WITH HIGH COMPOUND YIELD
Chengcang Charles WU¹, Andrea Stierle², Donald Stierle², Hongyu Chen¹, Peter Korajczyk¹, Rosa Ye¹, Jeremie Ferey¹ and Niel Mondava², (1)INTACT GENOMICS, INC, ST LOUIS, MO, USA, (2)University of Montana, Missoula, MT, USA

P104 – NOVEL BIOACTIVE PRENYLATED PHENOLS DERIVED FROM HETEROLOGOUS EXPRESSION OF A PSEUDOGYMNOASCUS DESTRUCTANS SQUALENE SYNTHASE GENE IN ASPERGILLUS NIDULANS
Dr. Sung Chul Park¹, Dr. Jin Woo Bok¹, Rosa Ye², Raveena Gupta³, Matthew Robey⁴, Dr. Chengcang Charles Wu², Prof. Neil Kelleher⁴ and Prof. Nancy P. Keller¹, (1)University of Wisconsin-Madison, Madison, WI, USA, (2)INTACT GENOMICS, INC, ST LOUIS, MO, USA, (3)Northwestern University, USA, (4)Northwestern University, Evanston, IL, USA

St. Louis Inno, an online division of St. Louis Business Journal focused on startups, entrepreneurs and trending companies, interviewed Intact Genomics founder Dr. Charles Wu to discuss our recent exciting news and SBIR grant success.
Find more information here:
https://lnkd.in/gjZF6gdu

On July 1, 2022, Intact Genomics announced that it has received a three-year Small Business Innovation Research (SBIR) Direct Phase II grant from the National Institute of Allergy and Infectious Diseases of the National Institute of Health. The total award is 2.94M. The company will develop new technology for rapid dissection of the biosynthesis of antiMRSA antibiotics produced in co-culture by extremophilic fungi through the development of Fungal Artificial Chromosomes (FACs).

“High through-put genome sequencing technologies opened the door for the discovery of natural products from filamentous fungi for therapeutic, agricultural, and other applications,” said Dr. Chengcang Charles Wu, founder, and CEO of Intact Genomics. “During a span of 50 years, from the 1940s to the 1990s, microbial natural product discovery provided the most important sources for fungicides, insecticides, antibiotics, anti-cancer agents, immune-modulators, and anthelminthic agents.  However, since the 1990s, microbial natural product discovery has become became less productive due to rediscovery issues, low throughput, and lack of relevant new technologies to unveil less abundant or not easily detected drug-like natural products. New discovery technologies of fungal natural products including antiMRSA antibiotics are urgently needed to meet the rapidly rising demand for anti-infectious, anticancer, and other therapeutic agents in the future. Sponsored by NIAID, Intact Genomics will collaborate with Dr. Andrea Stierle laboratory of the University of Montana to develop antiMRSA antibiotic biosynthesis to solve these problems.”

On June 28, 2022, Intact Genomics successfully graduated from Helix Center Biotech Incubator in St. Louis, Missouri, USA and moved to a nearby brand-new remodeled facility at 11840 Westline Industrial Drive.

Our new facility includes state-of-the-art laboratory areas and office area, meeting room and breakroom under one roof, allowing for seamless collaboration across functional teams. This new space provides our growing team with a quiet, safe, beautiful and inspiring workspace to develop cutting-edge technologies and provide better life science products and services for our customers around the world.

Intact Genomics Sponsored The 32nd International Conference on Arabidopsis Research (ICAR2022) on June 20-24 in Ireland. The International Conference on Arabidopsis Research (ICAR) is an annual gathering of up to thousand scientists whose primary research organism is the model plant Arabidopsis thaliana. This meeting embraces the remarkable contribution that Arabidopsis has made to our understanding of plant science.

Plant science can make big impacts on sustainable agriculture, forestry, environmental conservation, biodiversity protection and climate action, as well as in the production of nutritious food and plant-based non-food products – such as paper, timber, chemicals, energy and pharmaceuticals. Plant scientists contribute to a diverse range of key industries including agriculture, pharmaceuticals, forestry, food and biotechnology.

Intact Genomics is pleased to announce that as of June 22nd, 2022, our products will now be available for purchase in Brazil through our new distributor, LBF Comércio e Serviços Ltda.

Working with a complete line reagents for scientific research, LBF Biotechnologies has emerged in Brazil as a leader working with professionals with more than 23 years of experience in the market.

Our complete product portfolio is now available through LBF Biotechnologies. If you have any questions about ordering through one of our distributors please send your inquiries to [email protected] .

Visit us at Booth 1630, and talk with our sales director, Mr. Andy Robertson, and/or CEO, Dr. Chengcang Wu to learn more about our new products, services and technologies. We provide superior molecular biology research tools including agrobacterium competent cells, recombinase polymerase amplification (RPA) optimization enzymes, plant direct PCR kits, NGS supplies and custom genomic services to meet your research needs and serve worldwide plant and animal genome R&D community.

Dr. Chengcang Charles Wu, the inventor of Fungal Artificial Chromosome (FAC), spoke “Open New Door to Efficiently Discover Agricultural Chemicals and Drugs as Fungal Natural Products by Fungal Artificial Chromosome (FAC) Technology” at The 3rd Synthetic Biology of Natural Products Conference on May 19 in Cancun, Mexico.

Dr. Chengcang Charles Wu, founder and CEO of Intact Genomics, spoke at two workshops in PAG XXIX about our newly developed DirectPlate™ technology, which can transform more than 100kb DNA simply, efficiently and without electroporation.

“Analysis of Complex Genomes”
1:30 PM – 3:40 PM, Jan 8, 2022

“Functional Genomics ”
4:00 PM – 6:10 PM, Jan 9, 2022

Intact Genomics is pleased to announce that as of October 15th, 2021, our products will now be available for purchase in Taiwan, via our new distributer Protech Technology Enterprise Co., Ltd. For over 20 years, Protech has been a leader in the developing, manufacturing and marketing of premium quality life sciences solution in Taiwan and became a worldwide supplier.

i-DNA Biotechnology Pte Ltd becomes our new distributor in Singapore and Vietnam; and i-DNA Biotechnology (M) Sdn Bhd (663189-D) is our new distributor in Malaysia. i-DNA, a specialist in research solution, with the headquarter in Singapore and strong business network in the South-East Asia. Its primary focus is to develop, manufacture, market and distribute innovative products and services for applications in the area of life science, biotechnology and laboratory testing.

Our complete product portfolio is now available through Protech Technology Enterprise Co., Ltd and i-DNA Biotechnology. “Intact Genomics strives to provide high-quality products and services to our customers. We look forward to extend our business in Asian and grow our partnership with our distributors, ” says Andy Robertson, Director of Sales at Intact Genomics.