Intact Genomics CEO, Dr. Chengcang Charles Wu, will give a contributed talk of “Fungal Artificial Chromosome Pipeline Enables the Discovery of Novel Compounds from Unique Biosynthetic Gene Clusters” at the 2023 ASP Annual Meeting in Rockville, MD. The talk will be in the Fungal Biosynthesis and Chemodiversity session on Monday July 24th, 1:15pm – 3:25pm.
Intact Genomics changed its DNA arch logo to an exciting new “IG with DNA” design in April 2023. Our previous logo was designed by our founders when they started the company in St. Louis, Missouri. They were inspired by the adventure spirit of Gateway Arch and beauty of DNA. However, as we continue to grow, we believe that our new logo captures the essence of our vision for the future. IG® and Intact Genomics® are registered trademarks granted by the United States Patent and Trademark Office (USPTO) to Intact Genomics, Inc. The new logo features a modern, vibrant and dynamic design that reflects our commitment to innovation and staying current in the ever-changing business landscape. It embodies our company’s values of creativity, connectivity, and integrity, which align with the DNA of Intact Genomics.
At Plant & Animal Genome Conference (PAG) 30, hundreds of attendees visitted us at Booth 124, and talked with our VP of sales, Mr. Andy Robertson, and/or CEO, Dr. Chengcang Charles Wu to learn more about our new products, services and technologies. Intact Genomics provides superior molecular biology research products including agrobacterium competent cells, Quick10™ cloning kit, recombinase polymerase amplification (RPA) optimization enzymes, custom competent cells and custom genomic services to meet your research needs and serve the worldwide plant and animal genome R&D community.
Dr. Wu also presented “A novel DirectPlate® chemical competent cell technology ” within the workshop, “Development and Application of Genome Engineering and Transgenic Technology to the Agriculture.”
Intact Genomics had two poster presentations of our recent progresses on drug discovery R&D:
P84 – FUNGAL ARTIFICIAL CHROMOSOMES ACTIVATE THE CRYPTIC BIOSYNTHETIC GENE CLUSTER OF STROBILURINS, A POTENT AGRICULTURAL FUNGICIDE WITH HIGH COMPOUND YIELD
Chengcang Charles WU1, Andrea Stierle2, Donald Stierle2, Hongyu Chen1, Peter Korajczyk1, Rosa Ye1, Jeremie Ferey1 and Niel Mondava2, (1)INTACT GENOMICS, INC, ST LOUIS, MO, USA, (2)University of Montana, Missoula, MT, USA
P104 – NOVEL BIOACTIVE PRENYLATED PHENOLS DERIVED FROM HETEROLOGOUS EXPRESSION OF A PSEUDOGYMNOASCUS DESTRUCTANS SQUALENE SYNTHASE GENE IN ASPERGILLUS NIDULANS
Dr. Sung Chul Park1, Dr. Jin Woo Bok1, Rosa Ye2, Raveena Gupta3, Matthew Robey4, Dr. Chengcang Charles Wu2, Prof. Neil Kelleher4 and Prof. Nancy P. Keller1, (1)University of Wisconsin-Madison, Madison, WI, USA, (2)INTACT GENOMICS, INC, ST LOUIS, MO, USA, (3)Northwestern University, USA, (4)Northwestern University, Evanston, IL, USA
St. Louis Inno, an online division of St. Louis Business Journal focused on startups, entrepreneurs and trending companies, interviewed Intact Genomics founder Dr. Charles Wu to discuss our recent exciting news and SBIR grant success.
Find more information here:
https://lnkd.in/gjZF6gdu
On July 1, 2022, Intact Genomics announced that it has received a three-year Small Business Innovation Research (SBIR) Direct Phase II grant from the National Institute of Allergy and Infectious Diseases of the National Institute of Health. The total award is 2.94M. The company will develop new technology for rapid dissection of the biosynthesis of antiMRSA antibiotics produced in co-culture by extremophilic fungi through the development of Fungal Artificial Chromosomes (FACs).
“High through-put genome sequencing technologies opened the door for the discovery of natural products from filamentous fungi for therapeutic, agricultural, and other applications,” said Dr. Chengcang Charles Wu, founder, and CEO of Intact Genomics. “During a span of 50 years, from the 1940s to the 1990s, microbial natural product discovery provided the most important sources for fungicides, insecticides, antibiotics, anti-cancer agents, immune-modulators, and anthelminthic agents. However, since the 1990s, microbial natural product discovery has become became less productive due to rediscovery issues, low throughput, and lack of relevant new technologies to unveil less abundant or not easily detected drug-like natural products. New discovery technologies of fungal natural products including antiMRSA antibiotics are urgently needed to meet the rapidly rising demand for anti-infectious, anticancer, and other therapeutic agents in the future. Sponsored by NIAID, Intact Genomics will collaborate with Dr. Andrea Stierle laboratory of the University of Montana to develop antiMRSA antibiotic biosynthesis to solve these problems.”
On June 28, 2022, Intact Genomics successfully graduated from Helix Center Biotech Incubator in St. Louis, Missouri, USA and moved to a nearby brand-new remodeled facility at 11840 Westline Industrial Drive.
Our new facility includes state-of-the-art laboratory areas and office area, meeting room and breakroom under one roof, allowing for seamless collaboration across functional teams. This new space provides our growing team with a quiet, safe, beautiful and inspiring workspace to develop cutting-edge technologies and provide better life science products and services for our customers around the world.
Intact Genomics Sponsored The 32nd International Conference on Arabidopsis Research (ICAR2022) on June 20-24 in Ireland. The International Conference on Arabidopsis Research (ICAR) is an annual gathering of up to thousand scientists whose primary research organism is the model plant Arabidopsis thaliana. This meeting embraces the remarkable contribution that Arabidopsis has made to our understanding of plant science.
Plant science can make big impacts on sustainable agriculture, forestry, environmental conservation, biodiversity protection and climate action, as well as in the production of nutritious food and plant-based non-food products – such as paper, timber, chemicals, energy and pharmaceuticals. Plant scientists contribute to a diverse range of key industries including agriculture, pharmaceuticals, forestry, food and biotechnology.
Intact Genomics is pleased to announce that as of June 22nd, 2022, our products will now be available for purchase in Brazil through our new distributor, LBF Comércio e Serviços Ltda.
Working with a complete line reagents for scientific research, LBF Biotechnologies has emerged in Brazil as a leader working with professionals with more than 23 years of experience in the market.
Our complete product portfolio is now available through LBF Biotechnologies. If you have any questions about ordering through one of our distributors please send your inquiries to vendas@lbfcs.com.br .
Visit us at Booth 1630, and talk with our sales director, Mr. Andy Robertson, and/or CEO, Dr. Chengcang Wu to learn more about our new products, services and technologies. We provide superior molecular biology research tools including agrobacterium competent cells, recombinase polymerase amplification (RPA) optimization enzymes, plant direct PCR kits, NGS supplies and custom genomic services to meet your research needs and serve worldwide plant and animal genome R&D community.
