Intact Genomics (IG®, ig®) offers the largest collections of high-quality competent cells on the market.

Founded originally as a BAC cloning company, Intact Genomics developed deep expertise in producing ultra-high-efficiency competent cells to enable transformation of very large plasmids (~300 kb) into E. coli. Over the years, this expertise—combined with continuous process optimization—has allowed us to consistently deliver exceptionally high transformation efficiencies.

Leveraging our scientists’ expertise and craftsmanship, state-of-the-art equipment, advanced protocols, and rigorous quality control standards, our competent cells provide the following advantages:

• Highest Transformation Efficiency – Up to 10–100× higher than other leading brands.

• Quality Control – We maintain rigorous quality control measures in accordance with ISO 13485:2016 to ensure consistent reliability from batch to batch.
• Affordable– Competitive pricing to maximize your research budget.
• Format Flexibility & Custom Services Available – We offer a broader range of formats than competitors, including tubes (multiple aliquot sizes), 96- and 384-well plates, and strip tubes. We also provide custom competent cell services tailored to your specific needs.

Custom formats, custom package sizes and bulk pricing are available upon request.

Application	Product Link	Specialization	Efficiency
Cloning	IG 5-alpha Chemically Competent Cells	Routine cloning and sub-cloning, library construction	≥1.0 x 10^9
	IG 10B Chemically Competent Cells	Routine cloning and sub-cloning, library preparation including large DNA >10kb	≥1.0 x 10^10
	IG XL1 Blue Max Chemically Competent Cells	Stable plasmid propagation with blue/white screening	≥1.0 x 10^10
	HB101 Chemically Competent Cells	Stable plasmid maintenance	≥1.0 x 10^8
	JM109(DE3) Chemically Competent Cells	Cloning and T7 protein expression strain	≥1.0 x 10^8
	JM109 Chemically Competent Cells	Routine transformation and cloning	≥1.0 x 10^8
	MG1655 Chemically Competent Cells	“Wildtype” E coli strain	≥1.0 x 10^9
Specialized Cloning	IG Stable 2 Chemically Competent Cells	Cloning direct repeat sequences (unstable DNA)	≥1.0 x 10^9
	IG Recombineering Chemically Competent Cells	Homologous recombination, DNA, plasmid, and BAC engineering	≥1.0 x 10^9
	IG ccdB Resist™ Chemically Competent Cells	Propagation of plasmids containing the ccdB gene	≥1.0 x 10^9
Protein Expression	IG Autoinduction DE3 Chemically Competent Cells	Optimized for autoinduction of protein expression	≥3.0 x 10^7
	BL21(DE3) Chemically Competent Cells	Routine T7 protein expression	≥1.0 x 10^9
	BL21 Chemically Competent Cells	Routine non-T7 protein expression	≥1.0 x 10^9
	BL21(DE3)pLysS Chemically Competent Cells	T7 protein expression with tighter control for toxic proteins	≥3.0 x 10^7
	IG C41(DE3) Chemically Competent Cells	Improved expression of toxic proteins	≥3.0 x 10^7
	IG C41(DE3)pLysS Chemically Competent Cells	Improved expression of toxic proteins with suppressed basal expression	≥1.0 x 10^7
	IG C43(DE3) Chemically Competent Cells	Most tolerant of toxic proteins	≥3.0 x 10^7
	IG C43(DE3)pLysS Chemically Competent Cells	Most tolerant of toxic proteins with suppressed basal expression	≥5.0 x 10^6
	DL39(DE3) Chemically Competent Cells	Precise control over protein synthesis	≥1.0 x 10^7
Phage Display	ER2738 Phage Display Chemically Competent Cells	Preparation of antibody or peptide phage display libraries	≥1.0 x 10^10
Medium	IG Recovery Medium	Superior formulation for competent cell transformations	High-efficiency
	IG Autoinduction Medium	Directly promotes high-yield growth of E. coli and high-level expression of T7 promoter-regulated recombinant proteins	High-efficiency

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